From Readiness to Revenue
Building Sustainable Research Operations
We help transform compliant research sites into commercially successful operations — ready to attract new studies, strengthen sponsor relationships, and deliver measurable results.
Across the UK, many clinical teams are increasingly enthusiastic about entering commercial research but often lack a clear starting point.
They want to contribute to advancing science and improving patient access — yet navigating feasibility, governance, and sponsor engagement can feel complex and opaque.
At the same time, the UK faces a capacity challenge: despite strong demand from sponsors, the number of well-trained and commercially active research sites has plateaued.
By supporting new entrants and strengthening existing sites, ESMN Horizon is helping to expand national site capacity, accelerate study delivery, and enable more patients to participate in cutting-edge trials closer to home.
UK Clinical Research Capacity Snapshot
• Over 50% of GP practices express interest in commercial research, yet fewer than 10% are active participants.
• Sponsors report delays of 4–6 months in study start-up due to limited site availability.
• Increasing the pool of capable, research-ready sites could double patient access to commercial trials within five years.
(Sources: NIHR Site Alliance, ABPI, and independent industry reports.)
The Challenge: Untapped Commercial Potential
The Challenge: Untapped Commercial Potential
The Challenge: Untapped Commercial Potential
Operational Complexity: Navigating governance, compliance, and contracting can overwhelm clinical teams and delay study start-up.
Limited Capacity: Many sites lack the time, systems, or expertise to pursue and deliver more studies.
Unclear Commercial Strategy: Research capability often exists without a defined pathway to generate sustainable revenue or long-term partnerships.
Our Solution: Sustainable Growth
The Challenge: Untapped Commercial Potential
The Challenge: Untapped Commercial Potential
End-to-End Readiness: We establish compliant frameworks covering SOPs, governance, and team capability — laying the foundation for commercial success.
Strategic Growth Planning: We help sites define their business model, engage sponsors proactively, and expand their commercial portfolio.
Embedded Partnership: Through mentorship, advisory retainers, and business development support, we strengthen delivery capacity and drive long-term financial sustainability.
Our Measurable Impact
Faster Feasibility & Study Wins
Revenue Diversification via Commercial Trials
Faster Feasibility & Study Wins
Client: Large GP practice (newly research-active)
Challenge: Slow feasibility responses, missed PSVs, and limited commercial acumen.
Intervention: Commercial Research Manager-as-a-Service (RMaS) for feasibility tracking, PSV scheduling, and bid management.
Outcome: Turnaround time reduced from 10 days to 48 hours, win-rate up 60%, and clinical staff time protected.
Recruitment Performance Uplift
Revenue Diversification via Commercial Trials
Faster Feasibility & Study Wins
Client: Research-active Primary Care Network (PCN)
Challenge: Eligible patients not matched or converted efficiently.
Intervention: Recruitment Performance Framework — daily screening reports, dashboards, and investigator engagement routines.
Outcome: Recruitment doubled within six months, screen failures reduced by 25%, and the site invited to participate in two additional Phase III trials.
Revenue Diversification via Commercial Trials
Revenue Diversification via Commercial Trials
Revenue Diversification via Commercial Trials
Client: Independent GP practice (new to research)
Challenge: Reliant on NHS/QOF income with no commercial research pipeline.
Intervention: Readiness Accelerator programme with NCVR support, contract development, and targeted sponsor introductions.
Outcome: Three commercial studies secured in Year 1, generating £180,000+ in new annual revenue. ROI achieved after two studies.